Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects

Over the last few decades, mycotoxins, toxic fungal secondary metabolites that frequently contaminate foods and feeds, have attracted great interest at both scientific and industrial levels. The toxicity of these compounds has led to several regulations in many countries to control and quantify thes...

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Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2024
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description Over the last few decades, mycotoxins, toxic fungal secondary metabolites that frequently contaminate foods and feeds, have attracted great interest at both scientific and industrial levels. The toxicity of these compounds has led to several regulations in many countries to control and quantify these contaminants for their subsequent risk assessment. Many analytical methods have been developed, from rapid screening tests to mass spectrometry technology and the establishment of multi-mycotoxin-validated methods. At present, the food processing industry is looking for technologies to remove or reduce mycotoxins from food materials, with the aim of maintaining the nutritive value and palatability of the products treated. New non-destructive strategies, also known as innovative non-thermal food processing technologies, are being explored as an alternative to conventional thermal treatments for mycotoxin decontamination. The aim of the Special Issue “Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects” was to provide a space of exchange to address analytical methodology for mycotoxin determination for subsequent risk assessment as well as the identification of toxicological effects and the prevention of contamination. More specifically, the Special Issue covers two main aspects: experimental data and literature reviews. The methodology covered molecular methods for mycotoxin assessment to high-throughput mass spectrometry techniques with the inclusion of emerging mycotoxins in occurrence data and the use of computational methods in mycotoxin risk assessment.
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spelling doab-20.500.12854ir-1392422024-07-04T09:31:28Z Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects Berrada, Houda Ruiz Leal, María José genotoxicity liver S9 kidney S9 in vitro bioactivation toxigenic fungi ochratoxin A aflatoxins wheat rice maize oats breakfast cereals biocontrol food safety Fusarium graminearum mycotoxin water activity temperature transcriptome biopesticides cyclosporin C diamondback moth toxicity antifeedant activity fecundity enzyme activities bioaccessibility aflatoxin B1 zearalenone bread beetroot LC-Q-TOF-MS fumonisin B1 lanthanum chloride Clarias gariepinus hematology serum biochemistry space exposure entomopathogenic fungi pathogenicity secondary metabolites deoxynivalenol fumonisin tillage system nitrogen fertilisation crop diversification Fusarium Lumbricus terrestris brain hippocampus neurogenic niche neurotoxicity cell morphology lactic acid bacteria Aspergillus spp. Penicillium verrucosum fungal growth machine learning aflatoxin gastrointestinal tract natural adsorbent probiotic Saccharomyces cerevisiae Lactobacillus rhamnosus chocolate contamination chocolate safety alternative methods 3D culture spheroids in vitro toxicology mycotoxins aflatoxin M1 raw cow milk samples Tunisia HPLC-FD risk assessment thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology Over the last few decades, mycotoxins, toxic fungal secondary metabolites that frequently contaminate foods and feeds, have attracted great interest at both scientific and industrial levels. The toxicity of these compounds has led to several regulations in many countries to control and quantify these contaminants for their subsequent risk assessment. Many analytical methods have been developed, from rapid screening tests to mass spectrometry technology and the establishment of multi-mycotoxin-validated methods. At present, the food processing industry is looking for technologies to remove or reduce mycotoxins from food materials, with the aim of maintaining the nutritive value and palatability of the products treated. New non-destructive strategies, also known as innovative non-thermal food processing technologies, are being explored as an alternative to conventional thermal treatments for mycotoxin decontamination. The aim of the Special Issue “Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects” was to provide a space of exchange to address analytical methodology for mycotoxin determination for subsequent risk assessment as well as the identification of toxicological effects and the prevention of contamination. More specifically, the Special Issue covers two main aspects: experimental data and literature reviews. The methodology covered molecular methods for mycotoxin assessment to high-throughput mass spectrometry techniques with the inclusion of emerging mycotoxins in occurrence data and the use of computational methods in mycotoxin risk assessment. 2024-07-04T09:31:19Z 2024-07-04T09:31:19Z 2024 book ONIX_20240704_9783725808854_38 9783725808854 9783725808861 https://directory.doabooks.org/handle/20.500.12854/139242 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9237 https://mdpi.com/books/pdfview/book/9237 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-0886-1 10.3390/books978-3-7258-0886-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725808854 9783725808861 214 open access
spellingShingle genotoxicity
liver S9
kidney S9
in vitro
bioactivation
toxigenic fungi
ochratoxin A
aflatoxins
wheat
rice
maize
oats
breakfast cereals
biocontrol
food safety
Fusarium graminearum
mycotoxin
water activity
temperature
transcriptome
biopesticides
cyclosporin C
diamondback moth
toxicity
antifeedant activity
fecundity
enzyme activities
bioaccessibility
aflatoxin B1
zearalenone
bread
beetroot
LC-Q-TOF-MS
fumonisin B1
lanthanum chloride
Clarias gariepinus
hematology
serum biochemistry
space exposure
entomopathogenic fungi
pathogenicity
secondary metabolites
deoxynivalenol
fumonisin
tillage system
nitrogen fertilisation
crop diversification
Fusarium
Lumbricus terrestris
brain
hippocampus
neurogenic niche
neurotoxicity
cell morphology
lactic acid bacteria
Aspergillus spp.
Penicillium verrucosum
fungal growth
machine learning
aflatoxin
gastrointestinal tract
natural adsorbent
probiotic
Saccharomyces cerevisiae
Lactobacillus rhamnosus
chocolate contamination
chocolate safety
alternative methods
3D culture
spheroids
in vitro toxicology
mycotoxins
aflatoxin M1
raw cow milk samples
Tunisia
HPLC-FD
risk assessment
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology
Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects
title Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects
title_full Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects
title_fullStr Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects
title_full_unstemmed Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects
title_short Evaluation and Prevention of Mycotoxin Contamination and Toxicological Effects
title_sort evaluation and prevention of mycotoxin contamination and toxicological effects
topic genotoxicity
liver S9
kidney S9
in vitro
bioactivation
toxigenic fungi
ochratoxin A
aflatoxins
wheat
rice
maize
oats
breakfast cereals
biocontrol
food safety
Fusarium graminearum
mycotoxin
water activity
temperature
transcriptome
biopesticides
cyclosporin C
diamondback moth
toxicity
antifeedant activity
fecundity
enzyme activities
bioaccessibility
aflatoxin B1
zearalenone
bread
beetroot
LC-Q-TOF-MS
fumonisin B1
lanthanum chloride
Clarias gariepinus
hematology
serum biochemistry
space exposure
entomopathogenic fungi
pathogenicity
secondary metabolites
deoxynivalenol
fumonisin
tillage system
nitrogen fertilisation
crop diversification
Fusarium
Lumbricus terrestris
brain
hippocampus
neurogenic niche
neurotoxicity
cell morphology
lactic acid bacteria
Aspergillus spp.
Penicillium verrucosum
fungal growth
machine learning
aflatoxin
gastrointestinal tract
natural adsorbent
probiotic
Saccharomyces cerevisiae
Lactobacillus rhamnosus
chocolate contamination
chocolate safety
alternative methods
3D culture
spheroids
in vitro toxicology
mycotoxins
aflatoxin M1
raw cow milk samples
Tunisia
HPLC-FD
risk assessment
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology
topic_facet genotoxicity
liver S9
kidney S9
in vitro
bioactivation
toxigenic fungi
ochratoxin A
aflatoxins
wheat
rice
maize
oats
breakfast cereals
biocontrol
food safety
Fusarium graminearum
mycotoxin
water activity
temperature
transcriptome
biopesticides
cyclosporin C
diamondback moth
toxicity
antifeedant activity
fecundity
enzyme activities
bioaccessibility
aflatoxin B1
zearalenone
bread
beetroot
LC-Q-TOF-MS
fumonisin B1
lanthanum chloride
Clarias gariepinus
hematology
serum biochemistry
space exposure
entomopathogenic fungi
pathogenicity
secondary metabolites
deoxynivalenol
fumonisin
tillage system
nitrogen fertilisation
crop diversification
Fusarium
Lumbricus terrestris
brain
hippocampus
neurogenic niche
neurotoxicity
cell morphology
lactic acid bacteria
Aspergillus spp.
Penicillium verrucosum
fungal growth
machine learning
aflatoxin
gastrointestinal tract
natural adsorbent
probiotic
Saccharomyces cerevisiae
Lactobacillus rhamnosus
chocolate contamination
chocolate safety
alternative methods
3D culture
spheroids
in vitro toxicology
mycotoxins
aflatoxin M1
raw cow milk samples
Tunisia
HPLC-FD
risk assessment
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology
url ONIX_20240704_9783725808854_38